The Difrax Natural Anti-Colic S-Bottle 250ml is a BPA-free baby bottle built around two features Difrax has become known for: an anti-colic valve and the distinctive S-shaped body. Together they are designed to keep milk flowing steadily and the teat filled during a feed, so your baby can drink in comfortable, uninterrupted stretches while you hold them in a relaxed, natural position.
Suitable from birth and for both full-term and premature babies, this 250ml S-bottle is the follow-on size to the Natural S-Bottle 170ml, so you can move up to the larger capacity at around three months as your baby's feeds grow. It works with both breast milk and formula, which makes it a practical option if you are combining breastfeeding and bottle feeding, or transitioning between the two. It comes with the S-shaped bottle, a standard slow-flow S teat and a lid, ready to use straight away.
How the anti-colic S-bottle works
- Anti-colic valve: Designed to prevent vacuum from building up as your baby drinks and to limit the amount of air that mixes with the milk, helping keep the flow constant so feeds aren't interrupted by having to stop and reset the bottle.
- S-shaped body: The curved shape is designed to keep the teat filled with milk even when the bottle is held horizontally, which supports a more upright, natural feeding position for your baby.
- Slow-flow S teat: The standard-size teat is made from soft coated BPA-free silicone for extra grip and comfort, with a slow flow suited to newborns and early feeding.
- Air hole in the valve: A tiny air hole in the centre of the valve is what allows air in as milk flows out; keeping it open is what lets the bottle vent properly.
Easy to clean and fill
The base of the S-bottle unscrews, so you can open the bottle up at both ends for a more thorough clean, and reach the valve and inside of the bottle easily. The unscrewable base also makes it simple to drop in cubes of frozen breast milk. The bottle is made from lightweight, durable BPA-free polypropylene and is dishwasher safe.
How to use
Before each use, check that the tiny air hole in the centre of the valve is open by squeezing it several times. Check the teat daily by pulling firmly on it to make sure it is still intact and undamaged, and replace it if you notice any wear.
Best For
The Difrax Natural Anti-Colic S-Bottle 250ml is a great option for parents who:
- Want an anti-colic bottle they can use from birth, including with premature babies
- Are combining breastfeeding and bottle feeding, or moving between the two
- Prefer a bottle with an unscrewable base that opens up for easier cleaning
- Store and feed expressed breast milk, including frozen cubes
It may not be the best fit if you:
- Are looking for a faster teat flow for an older baby, as this comes with a slow-flow S teat
- Prefer a glass bottle over polypropylene
Pandylane Pro Tip: If you express, the S-bottle is compatible with the Difrax breast pump, so you can pump straight into the bottle instead of transferring milk between extra containers.
Care & Maintenance
Ergonomic shape stimulates natural nutritional posture
Ideal for combination bottle feeding and breastfeeding
Award-winning design developed by the Difrax medical team
Unscrewable base for easy cleaning and filling with frozen breast milk cubes
Compact size ideal for newborns and early feeding stages
- 1x Small Teat
- 1x 250ml S-Shaped Bottle
- 1x Bottle Lid