The Difrax Natural Anti-Colic S-Bottle 250ml 2 Pack is a duo pack of the well-known Difrax S-bottle, a baby bottle built around two design features: a curved, S-shaped body and an anti-colic valve in the base. It carries expressed milk or formula, works from birth, and is designed to keep milk flowing steadily to the teat so your baby can feed comfortably. Each bottle is made from lightweight, BPA-free polypropylene (PP) and comes fitted with a soft-coated, BPA-free silicone size S teat with a slow flow.
This 250ml version is the follow-up to the Natural S-bottle 170ml, so when your baby is around three months old and the smaller bottle no longer holds enough, you can move up to this size without changing bottle systems. Both use the same size S teat, which keeps the transition simple. It's a standard-neck bottle, and the duo pack gives you two bottles ready to rotate through your feeding and cleaning routine.
How the anti-colic S-bottle works
- Anti-colic valve: The valve in the base is designed to let air in without a vacuum forming as your baby drinks, which helps keep milk flowing steadily and is intended to reduce the air swallowed during a feed.
- S-shaped body: The curved shape keeps milk flowing to the teat even when the bottle is held closer to horizontal, so your baby doesn't have to tip their head back and can feed in a more natural, ergonomic position.
- Air kept away from the milk: The valve and S-shape together are designed to keep air from mixing into the milk during feeding.
- Small, easy-to-accept teat: The size S teat has a small shape and a soft silicone coating that offers extra grip and comfort, which many babies take to easily.
Easy to clean and fill
The base unscrews and the bottle can be taken apart from top to bottom, so you can reach every part when washing. The bottles are dishwasher safe. The unscrewable base is also handy if you store breast milk in cubes, as you can drop frozen breast milk straight into the bottle.
Made for combination feeding
The Difrax S-bottle can be used from birth and is intended to work alongside breastfeeding, making it a practical option if you're combining breast and bottle. If the standard size S teat empties too quickly for your baby, or you're feeding a baby who drinks fast or has reflux, the Natural bottles can also be used with Difrax dental bottle teats.
Best For
The Difrax Natural Anti-Colic S-Bottle 250ml is a great option for parents who:
- Want a bottle they can use from birth and continue with as baby grows past the 170ml size
- Are combining breastfeeding and bottle feeding and want a system that fits both
- Prefer a bottle that comes apart fully for thorough cleaning
- Store expressed breast milk in cubes and want an easy way to fill the bottle
It may not be the best fit if you:
- Prefer a wide-neck bottle or a glass or stainless steel body
- Want a single bottle rather than a duo pack
Good to know
Difrax S-bottles come in a range of colours, and the exact colours in this pack aren't guaranteed. We'll supply what's available — if you have a preference, please add it to your order notes and we'll do our best to accommodate it. As a general care step, check the teat daily by pulling firmly on it to make sure it hasn't become damaged, and replace it if you notice any wear.
Pandylane Pro Tip: Before each feed, give the valve a few squeezes to check that the tiny air hole in the centre is open — this is what keeps the flow steady and the anti-colic system doing its job.
Care & Maintenance
Ideal for combination feeding and breastfeeding
Award-winning design developed by the Difrax medical team
Small teat size makes it easy for babies to accept
Unscrewable base allows for easy cleaning and filling with frozen breast milk cubes
Compatible with dental bottle teats, recommended for babies with reflux or fast drinkers
BPA-Free
Dishwasher Safe
- 2x Small Teats
- 2x 250ml S-Shaped Bottles
- 2x Bottle Lids